How to Disable USB Devices in Windows?

Open Your Windows Registry then Try the following
1. Always backup your registry in case you mess up something
2. Open regedit and change the key value ‘Start’
of ‘HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\USbStor” to 4.
Value 4 – Storage USB devices are disabled
Value 3 – Storage USB devices are enabled